S. Zhao, R. Kumar, A. Sakai, M. Vetting, B. M. Wood, S. Brown, P. C. Babbitt, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson.  “Discovery of new enzymes and metabolic pathways using structure and genome context”, Nature, 502 (2013) 698-702.  Online  F1000  [News&Views:  M. J. Wargo, “Digging up enzyme functions“, Nature Chemical Biology (2013).]  [Discussed in PSI/Nature Knowledgbase]  PMC3966649


C.-H. Choi, B. A. Webb, M. Chimenti, M. P. Jacobson, and D. L. Barber.  “pH sensing by FAK-His58 regulates focal adhesion remodeling”, J. Cell. Biol., 202 (2013) 849-859.  [Commentary:  C. Lawson and D. D. Schlaepfer, “pHocal adhesion kinase regulation is on a FERM foundation”, J. Cell. Biol., 202 (2013) 833-836.]  [Commentary:  K. Legg, “Factoring pH into FAK phosphorylation”, Cell Migration Gateway.]  [F1000PMC3776353


T. Lukk, A. Sakai, C. Kalyanaraman, S. Brown, H. J. Imker, L. Song, A. A. Fedorov, E. V. Fedorov, R. Toro, B. Hillerich, R. Seidel, Y. Patskovsky, M. W. Vetting, S. K. Nair, P. C. Babbitt, S. C. Almo, J. A. Gerlt, and M. P. Jacobson.  “Computational prediction of the diversity of enzyme specificity among dipeptide epimerases in the enolase superfamily”.  PNAS, 109 (2012) 4122-4127. [F1000] [Discussion in PSI/Nature Knowledgebase] [Chemical&Engineering News] PMC3306705


T. R. White, C. M. Renzelman, A. C. Rand, T. Rezai, C. M. McEwen, V. M. Gelev, R. A. Turner, A. C. Rand, R. G. Linington, S. S. F. Leung, A. S. Kalgutkar, J. N. Bauman, Y. Zhang, S. Liras, D. A. Price, A. M. Mathiowetz, M. P. Jacobson, and R. S. Lokey. “On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds”, Nature Chemical Biology, 7 (2011) 810-817.  PMC3210067.  [Discussed in SciBX 4 (2011).]  F1000


C. Frantz, G. Barreiro, L. Dominguez, X. Chen, R. Eddy, J. Condeelis, M. J. S. Kelly, M. P. Jacobson and D. L. Barber.  “Cofilin is a pH Sensor for Actin Free Barbed End Formation”.  Journal of Cell Biology, 183 (2008) 865–879.  [“In this issue”:  “Cofilin activity is a total coincidence“, Journal of Cell Biology, 183 (2008) 753.]  Online  PMC2592832  F1000


L. Song, C. Kalyanaraman, A. A. Fedorov, E. V. Fedorov, M. E. Glasner, S. Brown, P. C. Babbitt, S. C. Almo, M. P. Jacobson, and J. A. Gerlt.  “Assignment and Prediction of Function in the Enolase Superfamily:  A Divergent N-Succinyl Amino Acid Racemase from Bacillus cereus“, Nature Chemical Biology, 3 (2007) 486–491.  [News&Views:  K. N. Allen, “Form finds function“, Nature Chemical Biology, 3 (2007) 452–453.]   [NIGMS “Biomedical Beat“]  F1000  Online