W. M. Hewitt, S. S. F. Leung, C. R. Pye, A. R. Ponkey, M. Bednarek, M. P. Jacobson, and R. S. Lokey. “Cell-permeable cyclic peptides from synthetic libraries inspired by natural products”, JACS, 137 (2015) 715-721. F1000 Pubmed
Tag Archives: F1000
114.
S. Zhao, R. Kumar, A. Sakai, M. Vetting, B. M. Wood, S. Brown, P. C. Babbitt, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson. “Discovery of new enzymes and metabolic pathways using structure and genome context”, Nature, 502 (2013) 698-702. Online F1000 [News&Views: M. J. Wargo, “Digging up enzyme functions“, Nature Chemical Biology (2013).] [Discussed in PSI/Nature Knowledgbase] PMC3966649
112.
C.-H. Choi, B. A. Webb, M. Chimenti, M. P. Jacobson, and D. L. Barber. “pH sensing by FAK-His58 regulates focal adhesion remodeling”, J. Cell. Biol., 202 (2013) 849-859. [Commentary: C. Lawson and D. D. Schlaepfer, “pHocal adhesion kinase regulation is on a FERM foundation”, J. Cell. Biol., 202 (2013) 833-836.] [Commentary: K. Legg, “Factoring pH into FAK phosphorylation”, Cell Migration Gateway.] [F1000] PMC3776353
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P. Kumar, M. Chimenti, H. Pemble, O. Thompson, M. P. Jacobson, and T. Wittmann. “Multisite phosphorylation modulates CLASP-EB1 interactions by disrupting arginine-glutamate salt bridge networks”, Journal of Biological Chemistry, 287 (2012) 17050-17064. Online F1000 PMC3366819
94.
J. R. Ingram, S. B. Rafi, L. Lambeth, I. Hsieh, D. Ruelas, K.C. Lim, J. Sakanari, C. S. Craik, M. P. Jacobson and J. H. McKerrow. “Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni“, PLoS Neglected Tropical Diseases, 6 (2012) e1589. PMC3317910 F1000
93.
T. Lukk, A. Sakai, C. Kalyanaraman, S. Brown, H. J. Imker, L. Song, A. A. Fedorov, E. V. Fedorov, R. Toro, B. Hillerich, R. Seidel, Y. Patskovsky, M. W. Vetting, S. K. Nair, P. C. Babbitt, S. C. Almo, J. A. Gerlt, and M. P. Jacobson. “Computational prediction of the diversity of enzyme specificity among dipeptide epimerases in the enolase superfamily”. PNAS, 109 (2012) 4122-4127. [F1000] [Discussion in PSI/Nature Knowledgebase] [Chemical&Engineering News] PMC3306705
87.
T. R. White, C. M. Renzelman, A. C. Rand, T. Rezai, C. M. McEwen, V. M. Gelev, R. A. Turner, A. C. Rand, R. G. Linington, S. S. F. Leung, A. S. Kalgutkar, J. N. Bauman, Y. Zhang, S. Liras, D. A. Price, A. M. Mathiowetz, M. P. Jacobson, and R. S. Lokey. “On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds”, Nature Chemical Biology, 7 (2011) 810-817. PMC3210067. [Discussed in SciBX 4 (2011).] F1000
74.
J. Wilbur, B. D. Sellers, M. P. Jacobson, R. Fletterick, and F. Brodsky. “Conformation switching of clathrin light chain regulates clathrin lattice assembly”, Developmental Cell, 18 (2010) 841-848. [‘Issue Highlight’] Online PMC2975025 F1000
61.
C. Frantz, G. Barreiro, L. Dominguez, X. Chen, R. Eddy, J. Condeelis, M. J. S. Kelly, M. P. Jacobson and D. L. Barber. “Cofilin is a pH Sensor for Actin Free Barbed End Formation”. Journal of Cell Biology, 183 (2008) 865–879. [“In this issue”: “Cofilin activity is a total coincidence“, Journal of Cell Biology, 183 (2008) 753.] Online PMC2592832 F1000
52.
L. Song, C. Kalyanaraman, A. A. Fedorov, E. V. Fedorov, M. E. Glasner, S. Brown, P. C. Babbitt, S. C. Almo, M. P. Jacobson, and J. A. Gerlt. “Assignment and Prediction of Function in the Enolase Superfamily: A Divergent N-Succinyl Amino Acid Racemase from Bacillus cereus“, Nature Chemical Biology, 3 (2007) 486–491. [News&Views: K. N. Allen, “Form finds function“, Nature Chemical Biology, 3 (2007) 452–453.] [NIGMS “Biomedical Beat“] F1000 Online
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M. P. Jacobson, R. A. Friesner, Z. Xiang, and B. Honig. “On the Role of Crystal Packing in Determining Protein Side Chain Conformations”, Journal of Molecular Biology, 320 (2002) 597–608. F1000
The Jacobson Laboratory at UCSF 