M. M. Armstrong, C. J. Freedman, J. E. Jung, Y. Zheng, C. Kalyanaraman, M. P. Jacobson, A. Simeonov, D. J. Maloney, K. van Leyen, A. Jadhav, and T. R. Holman. “A potent and selective inhibitor targeting human and murine 12/15-LOX”, Bioorg. Med. Chem., 24 (2016) 1183-1190. PMC4778748
Tag Archives: Infectious Disease
142.
T. Long, R. J. Neitz, R. Beasley, C. Kalyanaraman, B. M. Suzuki, M. P. Jacobson, C. Dissous, J. H. McKerrow, D. H. Drewry, W. J. Zuercher, R. Singh, and C. R. Caffrey. “Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni”, PLoS Negl. Trop. Dis., 10 (2016) e0004356. Open Access
117.
M. Ndao, M. Nath-Chowdhury, M. Sajid, V. Marcus, S. T. Mashiyama, J. Sakanari, E. Chow, Z. Mackey, K. M. Land, M. P. Jacobson, C. Kalyanaraman, J. H. McKerrow, M. J. Arrowood, C. R. Caffrey. “A cysteine protease inhibitor rescues mice from a lethal Cryptosporidium parvum infection”, Antimicrobial Agents and Chemotherapy, 57 (2013) 6063-6073. Online PMC3837922
105.
J. W. Choy, C. Bryant, C. M. Calvet, P. S. Doyle, S. S. Gunatilleke, S. S. F. Leung, K. K. H. Ang, S. Chen, J. Gut, J. A. Oses-Prieto, J. B. Johnston, M. R. Arkin, A. L. Burlingame, J. Taunton, M. P. Jacobson, J. M. McKerrow, L. M. Podust, and A. R. Renslo. “Chemical-Biological Characterization of a Cruzain Inhibitor Reveals a Second Target and a Mammalian Off-Target”. Beilstein J. Org. Chem, 9 (2013) 15-25. PMC3566858
94.
J. R. Ingram, S. B. Rafi, L. Lambeth, I. Hsieh, D. Ruelas, K.C. Lim, J. Sakanari, C. S. Craik, M. P. Jacobson and J. H. McKerrow. “Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni“, PLoS Neglected Tropical Diseases, 6 (2012) e1589. PMC3317910 F1000
77.
P. S. Doyle, C.-K. Chen, J. B. Johnston, S. Hopkins, S. S. F. Leung, M. P. Jacobson, J. C. Engel, J. H. McKerrow, L. M. Podust. “A Non-azole CYP51 Inhibitor Cures Chagas Disease in a Mouse Model of Acute Infection”, Antimicrobial Agents and Chemotherapy, 54 (2010) 2480-2488. PMC2876414
73.
C.-K. Chen, S. S. F. Leung, C. Guilbert, M. P. Jacobson, J. H. McKerrow, and L. M. Podust. “Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole”. PLoS Neglected Tropical Diseases, 4 (2010) e651. PMC2850312
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