B. M. Silber, J. R. Gever, S. Rao, Z. Li, A. R. Renslo, K. Widjaja, C. Wong, K. Giles, Y. Freyman, M. Elepano, J. J. Irwin, M. P. Jacobson, and S. B. Prusiner. “Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells”, Bioorg. Med Chem., 22 (2014) 1960-1972. PMC3984052
Tag Archives: Neurodegenerative Diseases
116.
B. M. Silber, J. R. Gever, Z. Li, A. Gallardo-Godoy, A. R. Renslo, K. Widjaja, J. J. Irwin, S. Rao, M. P. Jacobson, S. Ghaemmaghami, and S. B. Prusiner. “Antiprion compounds that reduce PrPSc levels in dividing and stationary-phase cells”, Bioorg. Med. Chem., 21 (2013) 7999-8012. Online PMC3984054
115.
D. Lu, K. Giles, Z. Li, S. Rao, E. Dolghih, J. R. Gever, M. Geva, M. Elepano, A. Oehler, C. Bryant, A. Renslo, M. P. Jacobson, S. J. DeArmond, B. M. Silber, and S. B. Prusiner. “Biaryl amides and hydrazones as therapeutics for prion disease in transgenic mice”, J. Pharmacol. Exp. Ther., 347 (2013) 325-338. Online PMC3807058
106.
Z. Li, B. M. Silber, S. Rao, J. Gever, C. Bryant, A. Gallardo-Godoy, E. Dolghih, K. Widjaja, M. Elepano, M. P. Jacobson, S. B. Prusiner and A. R. Renslo. “2-Aminothiazoles with Improved Pharmacotherapeutic Properties for Treatment of Prion Disease”, ChemMedChem, 8 (2013) 847-857. PMC3984044
103.
B. M. Silber, S. Rao, K. L. Fife, A. Gallardo-Godoy, A. R. Renslo, D. K. Dalvie, K. Giles, Y. Freyman, M. Elepano, J. R. Gever, B. Lam, M. P. Jacobson, Y. Huang, L. Z. Benet, S. B. Prusiner. “Pharmacokinetics and metabolism of 2-aminothiazoles with antiprion activity in mice”, Pharmaceutical Research, 30 (2013) 932-950. PMC3640342